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- Viral hepatitis: Inflammation of the liver caused by a viral infection can cause liver cells to become damaged and release increased levels of ALT into the bloodstream.
- Liver cirrhosis: Scarring of the liver that can result from chronic liver disease, such as alcoholism or nonalcoholic fatty liver disease, can cause the liver cells to become damaged and release increased levels of ALT.
- Acetaminophen overdose: Overdose of the pain reliever acetaminophen can cause liver damage and elevated levels of ALT.
- Fatty liver disease: Accumulation of fat in the liver can cause liver cells to become damaged and release increased levels of ALT.
- Alcoholic liver disease: Chronic alcohol consumption can cause liver damage and elevated levels of ALT.
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